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GMC Sierra 2500 Trucks for Sale near Des Moines, Iowa

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Less than $400,000
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Used 2025 GMC Sierra 2500 AT4 Crew Cab

$75,987
speed 21,604 mi
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl Chevrolet
Ankeny, IA (3.6 mi)
(515) 303-4821

Used 2013 GMC Sierra 2500 SLE Crew Cab

$25,920 List Price
$25,809
speed 134,062 mi
sell
Key features
  • Diesel
  • Turbocharged Diesel V8 6.6L/403
  • 4WD
location_on
Dewey Ford
Ankeny, IA (3.6 mi)
(515) 585-8206

Used 2024 GMC Sierra 2500 AT4 Crew Cab

$72,530 List Price
$70,940
speed 21,000 mi
sell
Key features
  • Gasoline
  • Gas V8 6.6L/
  • 4WD
location_on
Dewey Ford
Ankeny, IA (3.6 mi)
(515) 585-8206

Used 2016 GMC Sierra 2500 Base Crew Cab

$29,457 List Price
$24,500
speed 154,690 mi
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Stivers Ford Lincoln Waukee
Waukee, IA (16.5 mi)
(515) 852-5384

New 2026 GMC Sierra 2500 Denali Crew Cab

$82,639
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl GMC of Marshalltown
Marshalltown, IA (38.7 mi)
(641) 321-3575

New 2026 GMC Sierra 2500 AT4X Crew Cab

$99,025 MSRP
$92,093
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl GMC of Marshalltown
Marshalltown, IA (38.7 mi)
(641) 321-3575

New 2026 GMC Sierra 2500 SLT Crew Cab

$78,520
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl GMC of Marshalltown
Marshalltown, IA (38.7 mi)
(641) 321-3575

New 2026 GMC Sierra 2500 SLE Crew Cab

$69,740
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl GMC of Marshalltown
Marshalltown, IA (38.7 mi)
(641) 321-3575

New 2026 GMC Sierra 2500 Denali Ultimate Crew Cab

$103,694 MSRP
$98,509
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl GMC of Marshalltown
Marshalltown, IA (38.7 mi)
(641) 321-3575

New 2026 GMC Sierra 2500 SLT Crew Cab

$76,999
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl GMC of Marshalltown
Marshalltown, IA (38.7 mi)
(641) 321-3575

New 2026 GMC Sierra 2500 Denali Ultimate Crew Cab

$100,765 MSRP
$95,727
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl GMC of Marshalltown
Marshalltown, IA (38.7 mi)
(641) 321-3575

New 2026 GMC Sierra 2500 AT4X Crew Cab

$99,225 MSRP
$97,725
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl GMC of Marshalltown
Marshalltown, IA (38.7 mi)
(641) 321-3575

Used 2020 GMC Sierra 2500 Denali Crew Cab

$61,333
speed 33,018 mi
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Karl GMC of Marshalltown
Marshalltown, IA (38.7 mi)
(641) 321-3575

Used 2012 GMC Sierra 2500 SLE Crew Cab

$10,445
speed 223,744 mi
sell
Key features
  • Gas/E85
  • 4WD
  • Crew Cab
location_on
Rydell Chevrolet of Waterloo
Waterloo, IA (84.3 mi)
(319) 481-5561

Used 2025 GMC Sierra 2500 AT4 Crew Cab

$74,613
speed 9,139 mi
sell
Key features
  • Gasoline
  • 4WD
  • Crew Cab
location_on
Woodhouse Ford of Blair
Blair, NE (134.8 mi)
(402) 538-8308

Used 2005 GMC Sierra 2500 SLT Crew Cab

$23,500
speed 148,206 mi
sell
Key features
  • Diesel
  • 4WD
  • Crew Cab
location_on
Rochester Ford
Rochester, MN (174.4 mi)
(507) 710-1213

New 2026 GMC Sierra 2500 AT4 Crew Cab

$89,425.1
sell
Key features
  • Diesel
  • 6.6L Duramax Turbo-Diesel V8 engine
  • 4WD
location_on
Harry Brown's GMC
Faribault, MN (186.5 mi)
(507) 338-6766

New 2026 GMC Sierra 2500 Pro Crew Cab

$65,836.57
sell
Key features
  • Diesel
  • 6.6L Duramax Turbo-Diesel V8 engine
  • 4WD
location_on
Harry Brown's GMC
Faribault, MN (186.5 mi)
(507) 338-6766

New 2026 GMC Sierra 2500 AT4X Crew Cab

$99,025 MSRP
$95,280.03
sell
Key features
  • Diesel
  • 6.6L Duramax Turbo-Diesel V8 engine
  • 4WD
location_on
Harry Brown's GMC
Faribault, MN (186.5 mi)
(507) 338-6766

New 2026 GMC Sierra 2500 Pro Crew Cab

$66,029.27
sell
Key features
  • Diesel
  • 6.6L Duramax Turbo-Diesel V8 engine
  • 4WD
location_on
Harry Brown's GMC
Faribault, MN (186.5 mi)
(507) 338-6766

Used 2021 GMC Sierra 2500 Base Double Cab

$32,997
speed 85,527 mi
sell
Key features
  • Gasoline
  • Engine: 6.6L, V-8, SIDI
  • 4WD
location_on
Harry Brown's Chevrolet
Faribault, MN (186.5 mi)
(507) 203-2285

Used 2021 GMC Sierra 2500 Base Double Cab

$32,997
speed 85,527 mi
sell
Key features
  • Gasoline
  • Engine: 6.6L, V-8, SIDI
  • 4WD
location_on
Harry Brown's GMC
Faribault, MN (186.5 mi)
(507) 338-6766

Used 2019 GMC Sierra 2500 Denali Crew Cab

$32,997
speed 128,245 mi
sell
Key features
  • Gas/E85
  • Engine: 6.0L, V-8, SFI, FlexFuel w/ E63 only
  • 4WD
location_on
Harry Brown's GMC
Faribault, MN (186.5 mi)
(507) 338-6766

Used 2019 GMC Sierra 2500 Denali Crew Cab

$32,997
speed 128,245 mi
sell
Key features
  • Gas/E85
  • Engine: 6.0L, V-8, SFI, FlexFuel w/ E63 only
  • 4WD
location_on
Harry Brown's Chevrolet
Faribault, MN (186.5 mi)
(507) 203-2285

Used 2022 GMC Sierra 2500 Denali Crew Cab

$60,900
speed 38,380 mi
sell
Key features
  • Diesel
  • 6.6L Duramax Turbo-Diesel V8 engine
  • 4WD
location_on
Cable Dahmer Chevrolet of Independence
Independence, MO (186.7 mi)
(816) 542-3074

Used 2024 GMC Sierra 2500 AT4X Crew Cab

$72,900
speed 83,637 mi
sell
Key features
  • Diesel
  • 6.6L Duramax Turbo-Diesel V8 engine
  • 4WD
location_on
Cable Dahmer Chevrolet of Independence
Independence, MO (186.7 mi)
(816) 542-3074

Used 2022 GMC Sierra 2500 Denali Crew Cab

$53,249
speed 100,933 mi
sell
Key features
  • Diesel
  • 8 Cylinder Engine
  • 4x4
location_on
Dahl Ford Truck La Crosse
La Crosse, WI (191.4 mi)
(608) 747-7476

New 2026 GMC Sierra 2500 Denali Crew Cab

$91,680 MSRP
$82,180
sell
Key features
  • Diesel
  • 6.6L Duramax Turbo-Diesel V8 engine
  • 4WD
location_on
Cable Dahmer Buick GMC of Kansas City
Kansas City, MO (195.5 mi)
(816) 495-3524

New 2026 GMC Sierra 2500 Denali Crew Cab

$92,550 MSRP
$83,050
sell
Key features
  • Diesel
  • 6.6L Duramax Turbo-Diesel V8 engine
  • 4WD
location_on
Cable Dahmer Buick GMC of Kansas City
Kansas City, MO (195.5 mi)
(816) 495-3524

New 2026 GMC Sierra 2500 AT4X Crew Cab

$99,620
sell
Key features
  • Diesel
  • 6.6L Duramax Turbo-Diesel V8 engine
  • 4WD
location_on
Cable Dahmer Buick GMC of Kansas City
Kansas City, MO (195.5 mi)
(816) 495-3524

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